iSENESC
LABORATÓRIO DE INFLAMAÇÃO E SENESCÊNCIA CELULAR
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PseudoCell Database
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| ID | Node Symbol | Node Name | Node Centrality | Input Links (Kin) | Output Links (Kout) | Has Rules |
|---|---|---|---|---|---|---|
| 1 | AADeprivation | No node name found | 0 | 0 | 0 | No |
| 2 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 4 | 2 | 2 | Yes (1) |
| 3 | AFAP1 | actin filament associated protein 1 | 1 | 1 | 0 | Yes (1) |
| 4 | AKT1 | AKT serine/threonine kinase 1 | 28 | 12 | 16 | Yes (1) |
| 5 | AMPK | protein kinase AMP-activated catalytic subunit alpha 1 | 10 | 4 | 6 | Yes (1) |
| 6 | ANP32A | acidic nuclear phosphoprotein 32 family member A | 1 | 0 | 1 | No |
| 7 | APAF1 | apoptotic peptidase activating factor 1 | 2 | 1 | 1 | Yes (1) |
| 8 | ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 2 | 2 | 0 | Yes (1) |
| 9 | ARF1 | ADP ribosylation factor 1 | 0 | 0 | 0 | No |
| 10 | ARF5 | Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein | 0 | 0 | 0 | No |
| 11 | ARFGEF1 | ADP ribosylation factor guanine nucleotide exchange factor 1 | 0 | 0 | 0 | No |
| 12 | ARP2_3 | No node name found | 3 | 2 | 1 | Yes (1) |
| 13 | ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 5 | 5 | 0 | Yes (1) |
| 14 | ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 2 | 2 | 0 | Yes (1) |
| 15 | ATF2 | glial cell derived neurotrophic factor | 8 | 6 | 2 | Yes (1) |
| 16 | ATG1 | unc-51 like autophagy activating kinase 1 | 4 | 3 | 1 | Yes (1) |
| 17 | ATM | ATM serine/threonine kinase | 19 | 6 | 13 | Yes (2) |
| 18 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 | 3 | 2 | 1 | Yes (1) |
| 19 | ATP2A2 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 | 6 | 5 | 1 | Yes (1) |
| 20 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 | 0 | 0 | 0 | No |
| 21 | ATP2B1 | ATPase plasma membrane Ca2+ transporting 1 | 5 | 4 | 1 | Yes (2) |
| 22 | ATP2B2 | ATPase plasma membrane Ca2+ transporting 4 | 4 | 3 | 1 | Yes (2) |
| 23 | ATP2B3 | ATPase plasma membrane Ca2+ transporting 3 | 4 | 3 | 1 | Yes (2) |
| 24 | ATP2B4 | ATPase plasma membrane Ca2+ transporting 4 | 8 | 5 | 3 | Yes (2) |
| 25 | ATP2C1 | ATPase secretory pathway Ca2+ transporting 1 | 2 | 1 | 1 | Yes (1) |
| 26 | ATP2C2 | ATPase secretory pathway Ca2+ transporting 2 | 2 | 1 | 1 | Yes (1) |
| 27 | ATR | ATR serine/threonine kinase | 6 | 1 | 5 | Yes (1) |
| 28 | ActomyosinFibers | No node name found | 6 | 6 | 0 | Yes (1) |
| 29 | Apoptose | No node name found | 3 | 3 | 0 | Yes (1) |
| 30 | ArachidonicAcid | No node name found | 2 | 2 | 0 | Yes (1) |
| 31 | BAD | BCL2 associated agonist of cell death | 13 | 9 | 4 | Yes (2) |
| 32 | BAK | BCL2 antagonist/killer 1 | 5 | 4 | 1 | Yes (1) |
| 33 | BAX | BCL2 associated X, apoptosis regulator | 6 | 5 | 1 | Yes (1) |
| 34 | BCAR1 | BCAR1 scaffold protein, Cas family member | 1 | 1 | 0 | Yes (1) |
| 35 | BCL2 | BCL2 apoptosis regulator | 19 | 13 | 6 | Yes (9) |
| 36 | BCL2A1 | BCL2 related protein A1 | 8 | 6 | 2 | Yes (1) |
| 37 | BCL2L2 | BCL2 like 2 | 9 | 7 | 2 | Yes (1) |
| 38 | BCLXL | BCL2-like 1 | 14 | 11 | 3 | Yes (1) |
| 39 | BCR | BCR activator of RhoGEF and GTPase | 1 | 0 | 1 | No |
| 40 | BECN1 | beclin 1 | 2 | 2 | 0 | Yes (1) |
| 41 | BFL1 | BCL2 related protein A1 | 1 | 1 | 0 | Yes (1) |
| 42 | BID | BH3 interacting domain death agonist | 1 | 0 | 1 | No |
| 43 | BIK | BCL2 interacting killer | 3 | 0 | 3 | No |
| 44 | BIM | BCL2 like 11 | 12 | 5 | 7 | Yes (1) |
| 45 | BIRC2 | baculoviral IAP repeat containing 2 | 5 | 2 | 3 | Yes (1) |
| 46 | BIRC3 | baculoviral IAP repeat containing 3 | 5 | 2 | 3 | Yes (1) |
| 47 | BMF | BCL2 modifying factor | 3 | 0 | 3 | No |
| 48 | CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 4 | 3 | 1 | Yes (1) |
| 49 | CACNA1B | calcium channel, voltage-dependent, N type, alpha 1B subunit | 4 | 3 | 1 | Yes (1) |
| 50 | CACNA1C | calcium voltage-gated channel subunit alpha1 C | 4 | 3 | 1 | Yes (1) |
| 51 | CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 4 | 3 | 1 | Yes (1) |
| 52 | CACNA1E | calcium channel, voltage-dependent, R type, alpha 1E subunit | 4 | 3 | 1 | Yes (1) |
| 53 | CACNA1F | calcium voltage-gated channel subunit alpha1 F | 4 | 3 | 1 | Yes (1) |
| 54 | CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 2 | 1 | 1 | Yes (1) |
| 55 | CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit | 2 | 1 | 1 | Yes (1) |
| 56 | CACNA1I | calcium voltage-gated channel subunit alpha1 I | 2 | 1 | 1 | Yes (1) |
| 57 | CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit | 4 | 3 | 1 | Yes (1) |
| 58 | DFFB | DNA fragmentation factor subunit beta | 1 | 1 | 0 | Yes (1) |
| 59 | CALM1 | calmodulin 1 | 13 | 0 | 13 | No |
| 60 | CALR | calreticulin | 1 | 0 | 1 | No |
| 61 | CAMK2 | calcium/calmodulin-dependent protein kinase II delta | 4 | 1 | 3 | Yes (1) |
| 62 | CAPN1 | calpain 1 | 4 | 0 | 4 | No |
| 63 | CASK | calcium/calmodulin dependent serine protein kinase | 0 | 0 | 0 | No |
| 64 | CASP10 | caspase 10 | 5 | 2 | 3 | Yes (1) |
| 65 | CASP2 | caspase 2 | 4 | 2 | 2 | Yes (1) |
| 66 | CASP3 | caspase 3 | 8 | 4 | 4 | Yes (1) |
| 67 | CASP7 | caspase 7 | 6 | 4 | 2 | Yes (1) |
| 68 | CASP8 | caspase 8 | 7 | 2 | 5 | Yes (1) |
| 69 | CASP9 | caspase 9 | 5 | 3 | 2 | Yes (1) |
| 70 | CAT | catalase | 1 | 0 | 1 | No |
| 71 | CBL | Cbl proto-oncogene | 14 | 4 | 10 | Yes (1) |
| 72 | CBLB | Cbl proto-oncogene B | 0 | 0 | 0 | No |
| 73 | CBP | CREB binding protein | 1 | 0 | 1 | No |
| 74 | CCL11 | C-C motif chemokine ligand 11 | 4 | 1 | 3 | Yes (1) |
| 75 | CCL13 | C-C motif chemokine ligand 13 | 1 | 0 | 1 | No |
| 76 | CCL2 | C-C motif chemokine ligand 2 | 3 | 2 | 1 | Yes (1) |
| 77 | CCL24 | C-C motif chemokine ligand 24 | 1 | 0 | 1 | No |
| 78 | CCL26 | C-C motif chemokine ligand 26 | 1 | 0 | 1 | No |
| 79 | CCL3 | C-C motif chemokine ligand 3 | 1 | 0 | 1 | No |
| 80 | CCL5 | C-C motif chemokine ligand 5 | 2 | 0 | 2 | No |
| 81 | CCL7 | C-C motif chemokine ligand 7 | 3 | 0 | 3 | No |
| 82 | CCL8 | C-C motif chemokine ligand 8 | 1 | 0 | 1 | No |
| 83 | CCR1 | AMP-activated serine/threonine-protein kinase catalytic subunit SNF1 | 3 | 3 | 0 | Yes (1) |
| 84 | CCR2 | C-C motif chemokine receptor 2 | 4 | 3 | 1 | Yes (1) |
| 85 | CCR3 | C-C motif chemokine receptor 3 | 11 | 7 | 4 | Yes (1) |
| 86 | CCR5 | C-C motif chemokine receptor 5 | 2 | 1 | 1 | Yes (1) |
| 87 | CD200 | CD200 molecule | 1 | 0 | 1 | No |
| 88 | CD200R1 | CD200 receptor 1 | 3 | 2 | 1 | Yes (1) |
| 89 | CD22 | CD22 antigen | 8 | 1 | 7 | Yes (1) |
| 90 | CD2AP | CD2 associated protein | 3 | 1 | 2 | Yes (1) |
| 91 | CD300LF | CD300 molecule like family member F | 2 | 0 | 2 | No |
| 92 | CDC42 | cell division cycle 42 | 8 | 4 | 4 | Yes (1) |
| 93 | CDH1 | cadherin 1 | 1 | 0 | 1 | No |
| 94 | CDH2 | cadherin 2 | 1 | 0 | 1 | No |
| 95 | CDK2 | cyclin dependent kinase 2 | 6 | 3 | 3 | Yes (1) |
| 96 | CDK4_6 | No node name found | 4 | 2 | 2 | Yes (1) |
| 97 | CDKN1A | cyclin dependent kinase inhibitor 1A | 6 | 5 | 1 | Yes (1) |
| 98 | CDKN1B | cyclin dependent kinase inhibitor 1B | 2 | 2 | 0 | Yes (1) |
| 99 | CDKN2A | cyclin dependent kinase inhibitor 2A | 8 | 2 | 6 | Yes (1) |
| 100 | CEP78 | centrosomal protein 78 | 1 | 0 | 1 | No |
| 101 | CERS1 | growth differentiation factor 1 | 1 | 0 | 1 | No |
| 102 | CFL1 | cofilin 1 | 1 | 0 | 1 | No |
| 103 | CHEK1 | checkpoint kinase 1 | 5 | 2 | 3 | Yes (1) |
| 104 | CHEK2 | checkpoint kinase 2 | 4 | 3 | 1 | Yes (2) |
| 105 | CHUK | component of inhibitor of nuclear factor kappa B kinase complex | 2 | 2 | 0 | Yes (1) |
| 106 | CIB1 | dacapo | 1 | 0 | 1 | No |
| 107 | CIP2A | cellular inhibitor of PP2A | 3 | 2 | 1 | Yes (1) |
| 108 | CISH | cytokine inducible SH2 containing protein | 1 | 1 | 0 | Yes (1) |
| 109 | CIT | citron rho-interacting serine/threonine kinase | 1 | 1 | 0 | Yes (1) |
| 110 | CLEC4C | C-type lectin domain family 4 member C | 1 | 0 | 1 | No |
| 111 | CPP110 | No node name found | 0 | 0 | 0 | No |
| 112 | CRK | CRK proto-oncogene, adaptor protein | 4 | 2 | 2 | Yes (1) |
| 113 | CRKL | CRK like proto-oncogene, adaptor protein | 6 | 4 | 2 | Yes (1) |
| 114 | CSF1 | colony stimulating factor 1 (macrophage) | 1 | 0 | 1 | No |
| 115 | CSF1R | colony stimulating factor 1 receptor | 11 | 3 | 8 | Yes (1) |
| 116 | CSF3R | colony stimulating factor 3 receptor | 4 | 1 | 3 | Yes (1) |
| 117 | CSK | C-terminal Src kinase | 1 | 1 | 0 | Yes (1) |
| 118 | CSNK1A1 | casein kinase 1 alpha 1 | 1 | 0 | 1 | No |
| 119 | CXCL10 | C-X-C motif chemokine ligand 10 | 1 | 0 | 1 | No |
| 120 | CXCL12 | C-X-C motif chemokine ligand 12 | 1 | 0 | 1 | No |
| 121 | CXCL8 | C-X-C motif chemokine ligand 8 | 9 | 9 | 0 | Yes (1) |
| 122 | CXCR3 | C-X-C motif chemokine receptor 3 | 1 | 1 | 0 | Yes (1) |
| 123 | CXCR4 | C-X-C motif chemokine receptor 4 | 3 | 1 | 2 | Yes (1) |
| 124 | CYBA | cytochrome b-245 alpha chain | 3 | 2 | 1 | Yes (1) |
| 125 | CYBB | cytochrome b-245, beta polypeptide | 7 | 6 | 1 | Yes (1) |
| 126 | ComplexI | No node name found | 3 | 1 | 2 | Yes (1) |
| 127 | ComplexII | No node name found | 3 | 1 | 2 | Yes (1) |
| 128 | ComplexIII | No node name found | 4 | 2 | 2 | Yes (1) |
| 129 | ComplexIV | No node name found | 2 | 1 | 1 | Yes (1) |
| 130 | CtBP | C-terminal Binding Protein | 3 | 1 | 2 | Yes (1) |
| 131 | CytochromeC | No node name found | 2 | 1 | 1 | Yes (1) |
| 132 | CytochromeCRelease | No node name found | 4 | 2 | 2 | Yes (1) |
| 133 | DCAF1 | Chromatin assembly factor 1, p55 subunit | 1 | 0 | 1 | No |
| 134 | DCC | deleted in colorectal carcinoma | 3 | 2 | 1 | Yes (1) |
| 135 | DDB1 | damage specific DNA binding protein 1 | 1 | 0 | 1 | No |
| 136 | DIABLO | diablo IAP-binding mitochondrial protein | 4 | 1 | 3 | Yes (1) |
| 137 | DIAPH1 | diaphanous related formin 1 | 5 | 2 | 3 | Yes (1) |
| 138 | DNADamage | No node name found | 3 | 0 | 3 | No |
| 139 | DNAResection | No node name found | 0 | 0 | 0 | No |
| 140 | DOCK1 | dedicator of cytokinesis 1 | 2 | 1 | 1 | Yes (1) |
| 141 | DOK1 | docking protein 1 | 9 | 4 | 5 | Yes (1) |
| 142 | DOK2 | docking protein 2 | 5 | 2 | 3 | Yes (1) |
| 143 | DOK3 | docking protein 3 | 2 | 0 | 2 | No |
| 144 | DRAM1 | DNA damage regulated autophagy modulator 1 | 1 | 1 | 0 | Yes (1) |
| 145 | DSB | debris buster | 5 | 1 | 4 | Yes (2) |
| 146 | DSF | thiol:disulfide oxidoreductase DsbA | 1 | 0 | 1 | No |
| 147 | DUSP1 | dual specificity phosphatase 1 | 10 | 3 | 7 | Yes (1) |
| 148 | DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 2 | 0 | 2 | No |
| 149 | DYRK2 | dual specificity tyrosine phosphorylation regulated kinase 2 | 8 | 2 | 6 | Yes (1) |
| 150 | DYRK3 | dual specificity tyrosine phosphorylation regulated kinase 3 | 2 | 0 | 2 | No |
| 151 | E2F1 | E2F transcription factor 1 | 11 | 2 | 9 | Yes (1) |
| 152 | EDVPComplex | No node name found | 6 | 5 | 1 | Yes (1) |
| 153 | EGFR | epidermal growth factor receptor | 1 | 0 | 1 | No |
| 154 | EGLN3 | egl-9 family hypoxia inducible factor 3 | 0 | 0 | 0 | No |
| 155 | ELK1 | ETS transcription factor ELK1 | 7 | 6 | 1 | Yes (1) |
| 156 | ELK4 | GTP binding protein beta 1 | 7 | 6 | 1 | Yes (1) |
| 157 | ELMO1 | engulfment and cell motility 1 | 3 | 1 | 2 | Yes (1) |
| 158 | EPO | TIMP metallopeptidase inhibitor 1 | 2 | 1 | 1 | Yes (1) |
| 159 | EPOR | erythropoietin receptor | 9 | 2 | 7 | Yes (1) |
| 160 | ERK1 | mitogen-activated protein kinase 3 | 11 | 3 | 8 | Yes (1) |
| 161 | ERK2 | mitogen-activated protein kinase 1 | 13 | 3 | 10 | Yes (1) |
| 162 | FADD | Fas associated via death domain | 4 | 2 | 2 | Yes (1) |
| 163 | FAS | Fas cell surface death receptor | 8 | 7 | 1 | Yes (1) |
| 164 | FASL | Fas ligand | 6 | 5 | 1 | Yes (1) |
| 165 | FCER1G | Fc receptor, IgE, high affinity I, gamma polypeptide | 5 | 2 | 3 | Yes (1) |
| 166 | FCGR2B | Fc receptor, IgG, low affinity IIb | 1 | 0 | 1 | No |
| 167 | FGR | FGR proto-oncogene, Src family tyrosine kinase | 1 | 1 | 0 | Yes (1) |
| 168 | FIG4 | FIG4 phosphoinositide 5-phosphatase | 1 | 0 | 1 | No |
| 169 | FKBP1A | FKBP prolyl isomerase 1A | 3 | 0 | 3 | No |
| 170 | FKBP1B | FK506 binding protein 1b | 3 | 0 | 3 | No |
| 171 | FOS | FBJ osteosarcoma oncogene | 6 | 3 | 3 | Yes (1) |
| 172 | FOXK1 | forkhead box K1 | 2 | 2 | 0 | Yes (1) |
| 173 | FOXO3 | forkhead box O3 | 7 | 3 | 4 | Yes (1) |
| 174 | FOXP3 | forkhead box P3 | 1 | 0 | 1 | No |
| 175 | FXYD1 | FXYD domain-containing ion transport regulator 1 | 4 | 1 | 3 | Yes (1) |
| 176 | FYN | FYN proto-oncogene, Src family tyrosine kinase | 3 | 2 | 1 | Yes (1) |
| 177 | GAB1 | GRB2 associated binding protein 1 | 6 | 3 | 3 | Yes (1) |
| 178 | GAB2 | GRB2 associated binding protein 2 | 4 | 2 | 2 | Yes (1) |
| 179 | GABARAP | GABA type A receptor-associated protein | 3 | 3 | 0 | Yes (1) |
| 180 | GABARAPL2 | GABA type A receptor associated protein like 2 | 3 | 3 | 0 | Yes (1) |
| 181 | GPX1 | glutathione peroxidase 1 | 1 | 0 | 1 | No |
| 182 | GRB2 | growth factor receptor bound protein 2 | 14 | 8 | 6 | Yes (1) |
| 183 | GRB7 | growth factor receptor bound protein 7 | 1 | 1 | 0 | Yes (1) |
| 184 | GSK3A | shaggy | 4 | 0 | 4 | No |
| 185 | GSK3B | glycogen synthase kinase 3 beta | 8 | 2 | 6 | Yes (1) |
| 186 | GSR | glutathione-disulfide reductase | 1 | 0 | 1 | No |
| 187 | GYS1 | glycogen synthase 1 | 0 | 0 | 0 | No |
| 188 | H1 | DNA-binding transcriptional dual regulator H-NS | 2 | 1 | 1 | Yes (1) |
| 189 | H2AX | H2A.X variant histone | 4 | 3 | 1 | Yes (1) |
| 190 | HCK | HCK proto-oncogene, Src family tyrosine kinase | 6 | 1 | 5 | Yes (1) |
| 191 | HGF | interleukin 6 | 1 | 0 | 1 | No |
| 192 | HIPK2 | homeodomain interacting protein kinase 2 | 2 | 1 | 1 | Yes (1) |
| 193 | HIST2H2BE | H2B clustered histone 21 | 2 | 2 | 0 | Yes (1) |
| 194 | HIST3H3 | H3.4 histone, cluster member | 3 | 3 | 0 | Yes (1) |
| 195 | HOMER1 | homer scaffold protein 1 | 2 | 0 | 2 | No |
| 196 | HRK | harakiri, BCL2 interacting protein | 8 | 5 | 3 | Yes (1) |
| 197 | HSP90AA1 | heat shock protein 90 alpha family class A member 1 | 2 | 0 | 2 | No |
| 198 | HSPB1 | heat shock protein family B (small) member 1 | 4 | 2 | 2 | Yes (1) |
| 199 | HVA | No node name found | 7 | 0 | 7 | No |
| 200 | ICAD | DNA fragmentation factor subunit alpha | 4 | 3 | 1 | Yes (1) |
| 201 | IFNB1 | interferon beta 1 | 1 | 1 | 0 | Yes (1) |
| 202 | IGFBP1 | insulin like growth factor binding protein 1 | 1 | 1 | 0 | Yes (1) |
| 203 | IKBKG | inhibitor of nuclear factor kappa B kinase regulatory subunit gamma | 6 | 5 | 1 | Yes (1) |
| 204 | IL1A | interleukin 1 alpha | 3 | 1 | 2 | Yes (1) |
| 205 | IL1B | interleukin 1 beta | 3 | 1 | 2 | Yes (1) |
| 206 | IL1R1 | interleukin 1 receptor, type I | 8 | 6 | 2 | Yes (1) |
| 207 | IL1R2 | interleukin 1 receptor type 2 | 3 | 2 | 1 | Yes (1) |
| 208 | IL1RAP | interleukin 1 receptor accessory protein | 1 | 0 | 1 | No |
| 209 | IL1RN | interleukin 1 receptor antagonist | 2 | 1 | 1 | Yes (1) |
| 210 | IL34 | interleukin 34 | 1 | 0 | 1 | No |
| 211 | IL4 | interleukin 4 | 2 | 1 | 1 | Yes (1) |
| 212 | IL4R | interleukin 4 receptor | 9 | 1 | 8 | Yes (1) |
| 213 | IL6 | interleukin 6 | 5 | 4 | 1 | Yes (1) |
| 214 | IL6R | interleukin 6 receptor | 1 | 1 | 0 | Yes (1) |
| 215 | INPP4B | inositol polyphosphate-4-phosphatase type II B | 1 | 0 | 1 | No |
| 216 | INPP5D | inositol polyphosphate-5-phosphatase D | 25 | 20 | 5 | Yes (1) |
| 217 | INPPL1 | inositol polyphosphate phosphatase like 1 | 2 | 1 | 1 | Yes (1) |
| 218 | IP3R1 | inositol 1,4,5-trisphosphate receptor 1 | 3 | 2 | 1 | Yes (1) |
| 219 | IP3R2 | inositol 1,4,5-triphosphate receptor 2 | 3 | 2 | 1 | Yes (1) |
| 220 | IP3R3 | inositol 1,4,5-triphosphate receptor 3 | 3 | 2 | 1 | Yes (1) |
| 221 | IQSEC1 | IQ motif and Sec7 domain ArfGEF 1 | 0 | 0 | 0 | No |
| 222 | IRAK1 | interleukin 1 receptor associated kinase 1 | 10 | 3 | 7 | Yes (1) |
| 223 | IRAK2 | interleukin 1 receptor associated kinase 2 | 2 | 1 | 1 | Yes (1) |
| 224 | IRAK4 | interleukin 1 receptor associated kinase 4 | 7 | 1 | 6 | Yes (1) |
| 225 | IRS1 | insulin receptor substrate 1 | 9 | 7 | 2 | Yes (1) |
| 226 | JAK1 | Janus kinase 1 | 10 | 9 | 1 | Yes (1) |
| 227 | JAK2 | Janus kinase 2 | 34 | 25 | 9 | Yes (1) |
| 228 | JMY | junction mediating and regulatory protein, p53 cofactor | 1 | 1 | 0 | Yes (1) |
| 229 | JNK1 | mitogen-activated protein kinase 8 | 9 | 3 | 6 | Yes (1) |
| 230 | JNK2 | mitogen-activated protein kinase 9 | 9 | 3 | 6 | Yes (1) |
| 231 | JNK3 | mitogen-activated protein kinase 10 | 9 | 3 | 6 | Yes (1) |
| 232 | JUN | Jun proto-oncogene, AP-1 transcription factor subunit | 9 | 4 | 5 | Yes (1) |
| 233 | KAT5 | lysine acetyltransferase 5 | 7 | 1 | 6 | Yes (1) |
| 234 | KATNA1 | katanin catalytic subunit A1 | 0 | 0 | 0 | No |
| 235 | KCNIP3 | Kv channel interacting protein 3, calsenilin | 4 | 1 | 3 | Yes (1) |
| 236 | KHDRBS1 | KH RNA binding domain containing, signal transduction associated 1 | 1 | 1 | 0 | Yes (1) |
| 237 | KHSRP | KH-type splicing regulatory protein | 3 | 1 | 2 | Yes (1) |
| 238 | KIT | KIT proto-oncogene receptor tyrosine kinase | 6 | 1 | 5 | Yes (1) |
| 239 | KITLG | kit ligand | 1 | 0 | 1 | No |
| 240 | KLRG1 | killer cell lectin like receptor G1 | 4 | 2 | 2 | Yes (1) |
| 241 | LCK | LCK proto-oncogene, Src family tyrosine kinase | 1 | 0 | 1 | No |
| 242 | LCMT1 | leucine carboxyl methyltransferase 1 | 1 | 0 | 1 | No |
| 243 | LILRA4 | leukocyte immunoglobulin like receptor A4 | 1 | 0 | 1 | No |
| 244 | LIMK2 | LIM domain kinase 2 | 1 | 1 | 0 | Yes (1) |
| 245 | LVA | lava lamp | 3 | 0 | 3 | No |
| 246 | LYN | LYN proto-oncogene, Src family tyrosine kinase | 7 | 3 | 4 | Yes (1) |
| 247 | MAP1LC3A | microtubule associated protein 1 light chain 3 alpha | 3 | 3 | 0 | Yes (1) |
| 248 | MAP2K1 | mitogen-activated protein kinase kinase 1 | 3 | 1 | 2 | Yes (1) |
| 249 | MAP2K3 | mitogen-activated protein kinase kinase 3 | 5 | 2 | 3 | Yes (1) |
| 250 | MAP2K4 | mitogen-activated protein kinase kinase 4 | 9 | 3 | 6 | Yes (1) |
| 251 | MAP2K6 | mitogen-activated protein kinase kinase 6 | 5 | 2 | 3 | Yes (1) |
| 252 | MAP2K7 | hemipterous | 7 | 3 | 4 | Yes (1) |
| 253 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 3 | 2 | 1 | Yes (2) |
| 254 | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 5 | 0 | 5 | No |
| 255 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 1 | 0 | 1 | No |
| 256 | MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 14 | 8 | 6 | Yes (1) |
| 257 | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 1 | 0 | 1 | No |
| 258 | MAPK12 | mitogen-activated protein kinase 12 | 3 | 3 | 0 | Yes (1) |
| 259 | MAPK13 | mitogen-activated protein kinase 13 | 3 | 3 | 0 | Yes (1) |
| 260 | MAPKAPK2 | MAPK activated protein kinase 2 | 3 | 1 | 2 | Yes (1) |
| 261 | MCL1 | MCL1 apoptosis regulator, BCL2 family member | 5 | 3 | 2 | Yes (1) |
| 262 | MCU | mitochondrial calcium uniporter | 2 | 1 | 1 | Yes (1) |
| 263 | MDC1 | mediator of DNA damage checkpoint 1 | 3 | 2 | 1 | Yes (1) |
| 264 | MDM2 | MDM2 proto-oncogene | 6 | 5 | 1 | Yes (1) |
| 265 | MET | MET proto-oncogene, receptor tyrosine kinase | 10 | 1 | 9 | Yes (1) |
| 266 | MPO | myeloperoxidase | 1 | 0 | 1 | No |
| 267 | MRN | marionette | 3 | 2 | 1 | Yes (1) |
| 268 | MTM1 | myotubularin 1 | 2 | 0 | 2 | No |
| 269 | MTMR1 | myotubularin related protein 1 | 1 | 0 | 1 | No |
| 270 | MTMR2 | myotubularin related protein 2 | 2 | 0 | 2 | No |
| 271 | MTMR3 | myotubularin related protein 3 | 2 | 0 | 2 | No |
| 272 | MTMR6 | myotubularin related protein 6 | 1 | 0 | 1 | No |
| 273 | MYD88 | myeloid differentiation primary response gene 88 | 7 | 4 | 3 | Yes (1) |
| 274 | MYLK | myosin light chain kinase | 2 | 1 | 1 | Yes (1) |
| 275 | NCF1 | neutrophil cytosolic factor 1 | 5 | 1 | 4 | Yes (1) |
| 276 | NCF2 | neutrophil cytosolic factor 2 | 3 | 1 | 2 | Yes (1) |
| 277 | NCF4 | neutrophil cytosolic factor 4 | 2 | 1 | 1 | Yes (1) |
| 278 | NCK1 | NCK adaptor protein 1 | 1 | 1 | 0 | Yes (1) |
| 279 | NFATC1 | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 | 6 | 5 | 1 | Yes (1) |
| 280 | NFATC2 | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 | 3 | 3 | 0 | Yes (1) |
| 281 | NFATC3 | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 | 3 | 3 | 0 | Yes (1) |
| 282 | NFATC4 | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 | 4 | 4 | 0 | Yes (1) |
| 283 | Canonical_NFKB | No node name found | 17 | 3 | 14 | Yes (1) |
| 284 | NHEJ | No node name found | 2 | 2 | 0 | Yes (1) |
| 285 | NKRF | NFKB repressing factor | 3 | 0 | 3 | No |
| 286 | NOD1 | nucleotide binding oligomerization domain containing 1 | 1 | 0 | 1 | No |
| 287 | NOD2 | nucleotide binding oligomerization domain containing 2 | 2 | 1 | 1 | Yes (1) |
| 288 | NODosome | No node name found | 3 | 2 | 1 | Yes (1) |
| 289 | NOS1 | nitric oxide synthase 1, neuronal | 0 | 0 | 0 | No |
| 290 | NOS2 | nitric oxide synthase 2, inducible | 3 | 2 | 1 | Yes (1) |
| 291 | NOTCH1 | notch receptor 1 | 1 | 0 | 1 | No |
| 292 | NOXA | phorbol-12-myristate-13-acetate-induced protein 1 | 4 | 2 | 2 | Yes (1) |
| 293 | NR1I2 | nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 0 | No |
| 294 | NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 1 | 0 | 1 | No |
| 295 | NTN1 | netrin 1 | 5 | 0 | 5 | No |
| 296 | NuRDComplex | No node name found | 2 | 0 | 2 | No |
| 297 | ORAI1 | ORAI calcium release-activated calcium modulator 1 | 3 | 2 | 1 | Yes (1) |
| 298 | PIDD1 | p53-induced death domain protein 1 | 2 | 1 | 1 | Yes (1) |
| 299 | PARP1 | poly(ADP-ribose) polymerase 1 | 1 | 1 | 0 | Yes (1) |
| 300 | PCAF | lysine acetyltransferase 2B | 1 | 0 | 1 | No |
| 301 | PDE4D | phosphodiesterase 4D | 2 | 2 | 0 | Yes (1) |
| 302 | PDGFA | platelet derived growth factor subunit A | 2 | 0 | 2 | No |
| 303 | PDGFAA | platelet-derived growth factor alpha polypeptide a | 2 | 1 | 1 | Yes (1) |
| 304 | PDGFAB | platelet-derived growth factor alpha polypeptide b | 4 | 2 | 2 | Yes (1) |
| 305 | PDGFB | platelet derived growth factor subunit B | 4 | 2 | 2 | Yes (1) |
| 306 | PDGFBB | platelet-derived growth factor beta polypeptide b | 3 | 1 | 2 | Yes (1) |
| 307 | PDGFRA | platelet derived growth factor receptor, alpha polypeptide | 4 | 4 | 0 | Yes (1) |
| 308 | PDGFRB | platelet derived growth factor receptor beta | 3 | 3 | 0 | Yes (1) |
| 309 | PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 14 | 2 | 12 | Yes (1) |
| 310 | PDYN | prodynorphin | 0 | 0 | 0 | No |
| 311 | PECAM1 | platelet/endothelial cell adhesion molecule 1 | 1 | 0 | 1 | No |
| 312 | PELI1 | pellino 1 | 2 | 2 | 0 | Yes (1) |
| 313 | PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 2 | 2 | 0 | Yes (1) |
| 314 | PELI3 | pellino E3 ubiquitin protein ligase family member 3 | 2 | 2 | 0 | Yes (1) |
| 315 | PFN1 | profilin 1 | 2 | 1 | 1 | Yes (1) |
| 316 | PI3K | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 15 | 11 | 4 | Yes (1) |
| 317 | PIKFYVE | phosphoinositide kinase, FYVE-type zinc finger containing | 3 | 1 | 2 | Yes (1) |
| 318 | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 2 | 1 | 1 | Yes (1) |
| 319 | PKA | Protein kinase, cAMP-dependent, catalytic subunit 1 | 6 | 1 | 5 | Yes (1) |
| 320 | PKN1 | protein kinase N1 | 7 | 4 | 3 | Yes (1) |
| 321 | PKN2 | protein kinase N2 | 2 | 1 | 1 | Yes (1) |
| 322 | PKN2_F | No node name found | 5 | 2 | 3 | Yes (1) |
| 323 | PLA2G4A | phospholipase A2 group IVA | 4 | 3 | 1 | Yes (1) |
| 324 | PLA2G4C | phospholipase A2 group IVC | 4 | 3 | 1 | Yes (1) |
| 325 | PLCB2 | phospholipase C beta 2 | 3 | 1 | 2 | Yes (1) |
| 326 | PLCG1 | phospholipase C gamma 1 | 7 | 5 | 2 | Yes (1) |
| 327 | PLCG2 | phospholipase C gamma 2 | 3 | 1 | 2 | Yes (1) |
| 328 | PLN | phospholamban | 2 | 0 | 2 | No |
| 329 | PME1 | protein phosphatase methylesterase 1 | 1 | 0 | 1 | No |
| 330 | POU2F1 | POU class 2 homeobox 1 | 1 | 0 | 1 | No |
| 331 | PP1 | broad | 1 | 0 | 1 | No |
| 332 | PP2A | protein phosphatase 2 phosphatase activator | 18 | 9 | 9 | Yes (4) |
| 333 | PP2B | Calcineurin A1 | 8 | 4 | 4 | Yes (1) |
| 334 | PPM1D | protein phosphatase, Mg2+/Mn2+ dependent 1D | 7 | 1 | 6 | Yes (1) |
| 335 | PPP1CB | protein phosphatase 1 catalytic subunit beta | 2 | 1 | 1 | Yes (1) |
| 336 | PPP1R12A | protein phosphatase 1 regulatory subunit 12A | 1 | 0 | 1 | No |
| 337 | PPP1R13B | protein phosphatase 1 regulatory subunit 13B | 1 | 1 | 0 | Yes (1) |
| 338 | PRKCA | protein kinase C alpha | 8 | 3 | 5 | Yes (1) |
| 339 | PRKCB | protein kinase C beta | 1 | 1 | 0 | Yes (1) |
| 340 | PRKCD | protein kinase C delta | 4 | 2 | 2 | Yes (1) |
| 341 | PRKCE | protein kinase C epsilon | 2 | 1 | 1 | Yes (1) |
| 342 | PRKCH | protein kinase C eta | 1 | 1 | 0 | Yes (1) |
| 343 | PRKCZ | protein kinase C zeta | 7 | 4 | 3 | Yes (1) |
| 344 | PRKD1 | protein kinase D1 | 1 | 1 | 0 | Yes (1) |
| 345 | PRKDC | protein kinase, DNA activated, catalytic polypeptide | 3 | 2 | 1 | Yes (1) |
| 346 | PTEN | phosphatase and tensin homolog | 3 | 1 | 2 | Yes (1) |
| 347 | PTK2 | protein tyrosine kinase 2 | 2 | 1 | 1 | Yes (1) |
| 348 | PTPA | protein phosphatase 2 phosphatase activator | 1 | 0 | 1 | No |
| 349 | PTPN11 | protein tyrosine phosphatase non-receptor type 11 | 6 | 5 | 1 | Yes (1) |
| 350 | PTPN6 | protein tyrosine phosphatase non-receptor type 6 | 5 | 3 | 2 | Yes (1) |
| 351 | PUMA | BCL2 binding component 3 | 9 | 4 | 5 | Yes (1) |
| 352 | PURA | purine rich element binding protein A | 1 | 0 | 1 | No |
| 353 | PURB | purine rich element binding protein B | 1 | 0 | 1 | No |
| 354 | ProCASP10 | No node name found | 1 | 0 | 1 | No |
| 355 | ProCASP8 | No node name found | 1 | 0 | 1 | No |
| 356 | ProCASP9 | No node name found | 1 | 0 | 1 | No |
| 357 | RAC1 | Rac family small GTPase 1 | 10 | 7 | 3 | Yes (1) |
| 358 | RAC2 | Rac family small GTPase 2 | 5 | 2 | 3 | Yes (1) |
| 359 | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | 4 | 2 | 2 | Yes (1) |
| 360 | RAP1A | RAP1A, member of RAS oncogene family | 4 | 3 | 1 | Yes (1) |
| 361 | RAP2A | RAP2A, member of RAS oncogene family | 4 | 3 | 1 | Yes (1) |
| 362 | RAPGEF1 | Rap guanine nucleotide exchange factor 1 | 4 | 2 | 2 | Yes (1) |
| 363 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 | 4 | 1 | 3 | Yes (1) |
| 364 | RAS | Kirsten rat sarcoma viral oncogene homolog | 7 | 4 | 3 | Yes (1) |
| 365 | RASA1 | RAS p21 protein activator 1 | 4 | 4 | 0 | Yes (1) |
| 366 | RASSF1 | Ras association domain family member 1 | 1 | 1 | 0 | Yes (1) |
| 367 | RHOA | ras homolog family member A | 11 | 4 | 7 | Yes (1) |
| 368 | RHOG | Rac2 | 3 | 2 | 1 | Yes (1) |
| 369 | RIPK1 | receptor interacting serine/threonine kinase 1 | 10 | 7 | 3 | Yes (3) |
| 370 | RIPK2 | receptor interacting serine/threonine kinase 2 | 4 | 3 | 1 | Yes (1) |
| 371 | RND3 | Rho family GTPase 3 | 1 | 0 | 1 | No |
| 372 | RNF168 | ring finger protein 168 | 3 | 1 | 2 | Yes (1) |
| 373 | RNF8 | ring finger protein 8 | 2 | 1 | 1 | Yes (1) |
| 374 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | 3 | 2 | 1 | Yes (1) |
| 375 | ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 2 | 1 | 1 | Yes (1) |
| 376 | S6K1 | ribosomal protein S6 kinase B1 | 3 | 2 | 1 | Yes (1) |
| 377 | RYR1 | ryanodine receptor 1 | 9 | 7 | 2 | Yes (2) |
| 378 | RYR2 | ryanodine receptor 2, cardiac | 10 | 8 | 2 | Yes (2) |
| 379 | RYR3 | ryanodine receptor 3 | 7 | 5 | 2 | Yes (1) |
| 380 | Rb | RB transcriptional corepressor 1 | 4 | 3 | 1 | Yes (1) |
| 381 | S100A1 | S100 calcium binding protein A1 | 2 | 0 | 2 | No |
| 382 | SET | SET nuclear proto-oncogene | 3 | 2 | 1 | Yes (1) |
| 383 | SGK1 | serum/glucocorticoid regulated kinase 1 | 2 | 2 | 0 | Yes (1) |
| 384 | SGK2 | serum/glucocorticoid regulated kinase family member 3 | 2 | 2 | 0 | Yes (1) |
| 385 | SGK3 | serum/glucocorticoid regulated kinase family member 3 | 3 | 2 | 1 | Yes (1) |
| 386 | SGMS1 | sphingomyelin synthase 1 | 2 | 1 | 1 | Yes (1) |
| 387 | SH3KBP1 | SH3 domain containing kinase binding protein 1 | 4 | 1 | 3 | Yes (1) |
| 388 | SHC1 | SHC adaptor protein 1 | 11 | 6 | 5 | Yes (1) |
| 389 | SIAH1 | siah E3 ubiquitin protein ligase 1 | 3 | 2 | 1 | Yes (1) |
| 390 | SIAH2 | siah E3 ubiquitin protein ligase 2 | 3 | 1 | 2 | Yes (1) |
| 391 | SIRT1 | sirtuin 1 | 3 | 1 | 2 | Yes (1) |
| 392 | SLA2 | Sla2p | 1 | 1 | 0 | Yes (1) |
| 393 | SLC24A1 | solute carrier family 24 member 1 | 1 | 0 | 1 | No |
| 394 | SLC24A2 | solute carrier family 24 member 2 | 1 | 0 | 1 | No |
| 395 | SLC8A1 | solute carrier family 8 member A1 | 3 | 2 | 1 | Yes (1) |
| 396 | SLC8A1_n | No node name found | 4 | 3 | 1 | Yes (1) |
| 397 | SLC8A2 | solute carrier family 8 member A2 | 1 | 0 | 1 | No |
| 398 | SLC8A2_n | No node name found | 3 | 2 | 1 | Yes (1) |
| 399 | SLC8A3 | solute carrier family 8 member A3 | 1 | 0 | 1 | No |
| 400 | SLC8A3_n | No node name found | 3 | 2 | 1 | Yes (1) |
| 401 | SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 | 1 | 0 | 1 | No |
| 402 | SLN | sarcolipin | 2 | 0 | 2 | No |
| 403 | SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 1 | 0 | 1 | No |
| 404 | SOD1 | superoxide dismutase 1 | 1 | 0 | 1 | No |
| 405 | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1 | 3 | 1 | 2 | Yes (1) |
| 406 | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2 | 1 | 0 | 1 | No |
| 407 | SP1 | Sp1 transcription factor | 1 | 0 | 1 | No |
| 408 | SP3 | Sp3 transcription factor | 1 | 0 | 1 | No |
| 409 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 11 | 4 | 7 | Yes (1) |
| 410 | STAT1 | signal transducer and activator of transcription 1 | 3 | 2 | 1 | Yes (1) |
| 411 | STAT3 | signal transducer and activator of transcription 3 | 7 | 6 | 1 | Yes (2) |
| 412 | STAT5 | signal transducer and activator of transcription 5A | 2 | 2 | 0 | Yes (1) |
| 413 | STIM1 | stromal interaction molecule 1 | 2 | 1 | 1 | Yes (1) |
| 414 | STIM2 | stromal interaction molecule 2 | 2 | 1 | 1 | Yes (1) |
| 415 | SYK | spleen associated tyrosine kinase | 4 | 3 | 1 | Yes (1) |
| 416 | Starvation | No node name found | 0 | 0 | 0 | No |
| 417 | Survivin | baculoviral IAP repeat containing 5a | 3 | 1 | 2 | Yes (1) |
| 418 | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1 | 3 | 2 | 1 | Yes (1) |
| 419 | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2 | 4 | 3 | 1 | Yes (1) |
| 420 | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3 | 4 | 3 | 1 | Yes (1) |
| 421 | TEC | nuclear receptor subfamily 4, group A, member 3 | 2 | 1 | 1 | Yes (1) |
| 422 | TERT | telomerase reverse transcriptase | 7 | 7 | 0 | Yes (1) |
| 423 | TIAM1 | TIAM Rac1 associated GEF 1 | 3 | 1 | 2 | Yes (1) |
| 424 | TIP | lysine acetyltransferase 5 | 1 | 0 | 1 | No |
| 425 | TP53BP1 | tumor protein p53 binding protein 1 | 2 | 1 | 1 | Yes (1) |
| 426 | TP53BP2 | tumor protein p53 binding protein 2 | 1 | 1 | 0 | Yes (1) |
| 427 | TP53I3 | tumor protein p53 inducible protein 3 | 1 | 1 | 0 | Yes (1) |
| 428 | TP53INP1 | tumor protein p53 inducible nuclear protein 1 | 7 | 3 | 4 | Yes (1) |
| 429 | TP53INP2 | tumor protein p53 inducible nuclear protein 2 | 4 | 1 | 3 | Yes (1) |
| 430 | TRAF6 | TNF receptor associated factor 6 | 11 | 5 | 6 | Yes (1) |
| 431 | TRIM28 | tripartite motif containing 28 | 1 | 1 | 0 | Yes (1) |
| 432 | TSC2 | TSC complex subunit 2 | 6 | 5 | 1 | Yes (1) |
| 433 | UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 1 | 0 | 1 | No |
| 434 | UNC5A | unc-5 netrin receptor A | 1 | 1 | 0 | Yes (1) |
| 435 | UNC5B | unc-5 netrin receptor B | 1 | 1 | 0 | Yes (1) |
| 436 | UNC5C | unc-5 netrin receptor C | 1 | 1 | 0 | Yes (1) |
| 437 | UNC5D | unc-5 | 1 | 1 | 0 | Yes (1) |
| 438 | VAC14 | VAC14 component of PIKFYVE complex | 1 | 0 | 1 | No |
| 439 | VAV1 | vav guanine nucleotide exchange factor 1 | 5 | 0 | 5 | No |
| 440 | VAV2 | vav guanine nucleotide exchange factor 2 | 4 | 1 | 3 | Yes (1) |
| 441 | VMP1 | vacuole membrane protein 1 | 4 | 0 | 4 | No |
| 442 | VRK1 | VRK serine/threonine kinase 1 | 1 | 0 | 1 | No |
| 443 | WAS | WASP actin nucleation promoting factor | 4 | 3 | 1 | Yes (1) |
| 444 | WASF1 | WASP family member 1 | 1 | 0 | 1 | No |
| 445 | WASL | WASP like actin nucleation promoting factor | 2 | 2 | 0 | Yes (1) |
| 446 | WIPF1 | WAS/WASL interacting protein family member 1 | 1 | 1 | 0 | Yes (1) |
| 447 | XIAP | X-linked inhibitor of apoptosis | 0 | 0 | 0 | No |
| 448 | YBX1 | Y-box binding protein 1 | 1 | 0 | 1 | No |
| 449 | ZFP36 | ZFP36 ring finger protein | 3 | 1 | 2 | Yes (1) |
| 450 | mTORC1 | Mechanistic Target Of Rapamycin Kinase | 16 | 7 | 9 | Yes (1) |
| 451 | mTORC2 | No node name found | 6 | 1 | 5 | Yes (1) |
| 452 | mir155 | microRNA 155 | 1 | 0 | 1 | No |
| 453 | EP300 | E1A binding protein p300 | 4 | 3 | 1 | Yes (1) |
| 454 | MAPK14 | mitogen-activated protein kinase 14 | 22 | 7 | 15 | Yes (1) |
| 455 | TP53 | tumor protein p53 | 46 | 27 | 19 | Yes (17) |
| 456 | sIL1R1 | No node name found | 0 | 0 | 0 | No |
| 457 | sIL1R2 | No node name found | 0 | 0 | 0 | No |
| 458 | sIL1RAP | No node name found | 1 | 0 | 1 | No |
| 459 | tBID | No node name found | 14 | 9 | 5 | Yes (1) |
| 460 | Apigenin | No node name found | 0 | 0 | 0 | No |
| 461 | SSB | small RNA binding exonuclease protection factor La | 1 | 0 | 1 | No |
| 462 | CBX4 | chromobox 4 | 2 | 1 | 1 | Yes (1) |
| 463 | PIAS3 | protein inhibitor of activated STAT 3 | 2 | 1 | 1 | Yes (1) |
| 464 | CDC25A | cell division cycle 25A | 1 | 0 | 1 | No |
| 465 | CDC25B | cell division cycle 25B | 0 | 0 | 0 | No |
| 466 | CDC25C | string | 5 | 4 | 1 | Yes (1) |
| 467 | CDK1 | cyclin dependent kinase 1 | 5 | 2 | 3 | Yes (1) |
| 468 | CCND | cyclin D | 2 | 2 | 0 | Yes (1) |
| 469 | CCNE | cyclin E1 | 3 | 1 | 2 | Yes (1) |
| 470 | CCNA | cyclin A2 | 2 | 1 | 1 | Yes (1) |
| 471 | DNAReplication | No node name found | 3 | 2 | 1 | Yes (1) |
| 472 | WEE1 | WEE1 G2 checkpoint kinase | 2 | 1 | 1 | Yes (1) |
| 473 | HIF1 | hypoxia inducible factor 1 subunit alpha | 4 | 2 | 2 | Yes (1) |
| 474 | PSMC3 | proteasome 26S subunit, ATPase 3 | 1 | 0 | 1 | No |
| 475 | HMGB1 | high mobility group box 1 | 1 | 0 | 1 | No |
| 476 | AGER | advanced glycosylation end-product specific receptor | 16 | 7 | 9 | Yes (2) |
| 477 | S100B | S100 calcium binding protein B | 1 | 0 | 1 | No |
| 478 | S100P | S100 calcium binding protein B | 1 | 0 | 1 | No |
| 479 | CD36 | CD36 molecule (CD36 blood group) | 1 | 1 | 0 | Yes (1) |
| 480 | ITGAM | integrin alpha M | 1 | 0 | 1 | No |
| 481 | CTLA4 | cytotoxic T-lymphocyte associated protein 4 | 1 | 1 | 0 | Yes (1) |
| 482 | IL12R | interleukin 12 receptor subunit beta 1 | 1 | 0 | 1 | No |
| 483 | AGT | angiotensinogen | 1 | 0 | 1 | No |
| 484 | AGTR1 | angiotensin II receptor type 1 | 3 | 1 | 2 | Yes (1) |
| 485 | BRCA1 | BRCA1 DNA repair associated | 4 | 2 | 2 | Yes (1) |
| 486 | CRLF2 | cytokine receptor-like factor 2 | 1 | 0 | 1 | No |
| 487 | CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 1 | 0 | 1 | No |
| 488 | JAK3 | Janus kinase 3 | 2 | 2 | 0 | Yes (1) |
| 489 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 1 | 0 | 1 | No |
| 490 | FES | FES proto-oncogene, tyrosine kinase | 1 | 1 | 0 | Yes (1) |
| 491 | GHR | growth hormone receptor | 5 | 1 | 4 | Yes (1) |
| 492 | TYK2 | tyrosine kinase 2 | 4 | 4 | 0 | Yes (1) |
| 493 | GH1 | growth hormone 1 | 1 | 0 | 1 | No |
| 494 | HES1 | hes family bHLH transcription factor 1 | 1 | 0 | 1 | No |
| 495 | HES2 | hes family bHLH transcription factor 2 | 1 | 0 | 1 | No |
| 496 | HTR2A | 5-hydroxytryptamine receptor 2A | 2 | 0 | 2 | No |
| 497 | PLCB1 | phospholipase C beta 1 | 1 | 1 | 0 | Yes (1) |
| 498 | IFNGR | interferon gamma receptor 1 | 4 | 0 | 4 | No |
| 499 | IGF1R | insulin like growth factor 1 receptor | 4 | 1 | 3 | Yes (1) |
| 500 | SOCS1 | suppressor of cytokine signaling 1 | 3 | 1 | 2 | Yes (1) |
| 501 | IRF1 | interferon regulatory factor 1 | 2 | 1 | 1 | Yes (1) |
| 502 | IL23R | interleukin 23 receptor | 2 | 0 | 2 | No |
| 503 | IL3R | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 2 | 0 | 2 | No |
| 504 | IL13R | interleukin 13 receptor subunit alpha 2 | 4 | 1 | 3 | Yes (1) |
| 505 | IL5R | interleukin 5 receptor subunit alpha | 2 | 0 | 2 | No |
| 506 | INSR | insulin receptor | 1 | 0 | 1 | No |
| 507 | TIRAP | TIR domain containing adaptor protein | 3 | 2 | 1 | Yes (1) |
| 508 | FOXO4 | forkhead box O4 | 1 | 0 | 1 | No |
| 509 | FOXO1 | forkhead box O1 | 0 | 0 | 0 | No |
| 510 | MSN | moesin | 1 | 1 | 0 | Yes (1) |
| 511 | TNF | tumor necrosis factor | 2 | 0 | 2 | No |
| 512 | TNFRSF1A | tumor necrosis factor receptor superfamily, member 1a | 3 | 1 | 2 | Yes (1) |
| 513 | TNFRSF1B | tumor necrosis factor receptor superfamily, member 1b | 3 | 1 | 2 | Yes (1) |
| 514 | TRADD | TNFRSF1A associated via death domain | 4 | 1 | 3 | Yes (1) |
| 515 | TRAF2 | TNF receptor associated factor 2 | 6 | 3 | 3 | Yes (1) |
| 516 | TRAF5 | TNF receptor associated factor 5 | 1 | 1 | 0 | Yes (1) |
| 517 | CYLD | CYLD lysine 63 deubiquitinase | 4 | 2 | 2 | Yes (1) |
| 518 | TRAF1 | TNF receptor associated factor 1 | 1 | 1 | 0 | Yes (1) |
| 519 | AMP | adenine phosphoribosyltransferase | 0 | 0 | 0 | No |
| 520 | Ca_c | No node name found | 40 | 19 | 21 | Yes (8) |
| 521 | Ca_ec | No node name found | 8 | 8 | 0 | Yes (4) |
| 522 | Ca_er | No node name found | 10 | 5 | 5 | Yes (2) |
| 523 | Ca_g | No node name found | 2 | 2 | 0 | Yes (1) |
| 524 | Ca_m | No node name found | 1 | 1 | 0 | Yes (1) |
| 525 | Ca_n | No node name found | 4 | 3 | 1 | Yes (1) |
| 526 | Ceramide | No node name found | 4 | 2 | 2 | Yes (2) |
| 527 | DAG | clusterin | 5 | 4 | 1 | Yes (4) |
| 528 | Fumarate | No node name found | 1 | 1 | 0 | Yes (1) |
| 529 | GM1 | coenzyme Q10A | 3 | 0 | 3 | No |
| 530 | GSH | pyrimidodiazepine synthase | 1 | 1 | 0 | Yes (1) |
| 531 | GSSG | No node name found | 0 | 0 | 0 | No |
| 532 | H2O | No node name found | 4 | 4 | 0 | Yes (7) |
| 533 | H2O2 | No node name found | 1 | 1 | 0 | Yes (2) |
| 534 | HOCl | No node name found | 1 | 1 | 0 | Yes (1) |
| 535 | IP3 | internal virion protein | 6 | 3 | 3 | Yes (3) |
| 536 | MDP | dipeptidase 1 | 1 | 0 | 1 | No |
| 537 | NAD | Alt-like RNA polymerase ADP-ribosyltransferase | 1 | 1 | 0 | Yes (1) |
| 538 | NADH | NADH oxidase | 1 | 0 | 1 | No |
| 539 | NADP | No node name found | 1 | 1 | 0 | Yes (2) |
| 540 | NADPH | 2,4-dienoyl-CoA reductase 1 | 0 | 0 | 0 | No |
| 541 | NitricOxide | No node name found | 5 | 0 | 5 | No |
| 542 | OH | obstructive hydrocephalus | 0 | 0 | 0 | No |
| 543 | Oxygen | No node name found | 1 | 0 | 1 | No |
| 544 | PI345P | No node name found | 5 | 1 | 4 | Yes (1) |
| 545 | PI34P | No node name found | 5 | 3 | 2 | Yes (3) |
| 546 | PI35P | No node name found | 1 | 1 | 0 | Yes (1) |
| 547 | PI3P | No node name found | 3 | 3 | 0 | Yes (3) |
| 548 | PI45P | No node name found | 7 | 1 | 6 | Yes (1) |
| 549 | PI5P | No node name found | 4 | 4 | 0 | Yes (4) |
| 550 | Peroxynitrite | No node name found | 2 | 2 | 0 | Yes (2) |
| 551 | PtdIns | No node name found | 5 | 5 | 0 | Yes (5) |
| 552 | Succinate | No node name found | 1 | 0 | 1 | No |
| 553 | Superoxide | No node name found | 8 | 0 | 8 | No |
| 554 | Ubiquinol | No node name found | 4 | 2 | 2 | Yes (1) |
| 555 | Ubiquinone | No node name found | 1 | 1 | 0 | Yes (2) |
| 556 | Ubisemiquinone | No node name found | 3 | 2 | 1 | Yes (3) |
| 557 | cAMP | cyclic adenosine monophosphate | 2 | 0 | 2 | No |
| 558 | G1_Phase | No node name found | 2 | 1 | 1 | Yes (1) |
| 559 | S_Phase | No node name found | 4 | 3 | 1 | Yes (1) |
| 560 | G2_Phase | No node name found | 3 | 2 | 1 | Yes (1) |
| 561 | Mitosis | No node name found | 3 | 2 | 1 | Yes (1) |
| 562 | MitosisStimule | No node name found | 2 | 0 | 2 | No |
| 563 | AGE | renin binding protein | 2 | 0 | 2 | No |
| 564 | FRAT1 | FRAT regulator of WNT signaling pathway 1 | 1 | 0 | 1 | No |
| 565 | TP53RK | TP53 regulating kinase | 2 | 1 | 1 | Yes (1) |
| 566 | Rapamycin | No node name found | 1 | 0 | 1 | No |
| 567 | EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2 | 1 | 1 | Yes (1) |
| 568 | EIF4F | eukaryotic translation initiation factor 4E | 1 | 1 | 0 | Yes (1) |
| 569 | RHEB | Ras homolog enriched in brain | 0 | 0 | 0 | No |
| 570 | STK11 | serine/threonine kinase 11 | 5 | 2 | 3 | Yes (1) |
| 571 | TSC1 | TSC complex subunit 1 | 5 | 4 | 1 | Yes (1) |
| 572 | RSK | ribosomal protein S6 kinase A3 | 4 | 2 | 2 | Yes (1) |
| 573 | NF1 | neurofibromin 1 | 2 | 1 | 1 | Yes (1) |
| 574 | NFKBIA | NFKB inhibitor alpha | 2 | 1 | 1 | Yes (1) |
| 575 | IKK | kenny | 3 | 2 | 1 | Yes (1) |
| 576 | NonCanonical_NFKB | No node name found | 2 | 1 | 1 | Yes (1) |
| 577 | P100 | nuclear factor kappa B subunit 2 | 2 | 1 | 1 | Yes (1) |
| 578 | NIK | mitogen-activated protein kinase kinase kinase 14 | 2 | 1 | 1 | Yes (1) |
| 579 | TRAF3 | TNF receptor associated factor 3 | 2 | 1 | 1 | Yes (1) |
| 580 | LTBR | lymphotoxin B receptor | 3 | 2 | 1 | Yes (1) |
| 581 | LTA | lymphotoxin alpha | 1 | 0 | 1 | No |
| 582 | LTB | lymphotoxin B | 1 | 0 | 1 | No |
| 583 | PTGS2 | prostaglandin-endoperoxide synthase 2 | 1 | 1 | 0 | Yes (1) |
| 584 | IGF1 | insulin like growth factor 1 | 1 | 0 | 1 | No |
| 585 | GlucoseDeprivation | No node name found | 1 | 0 | 1 | No |
| 586 | Hypoxia | No node name found | 1 | 0 | 1 | No |
| 587 | DDIT4 | DNA damage inducible transcript 4 | 4 | 2 | 2 | Yes (1) |
| 588 | GRB10 | growth factor receptor bound protein 10 | 2 | 1 | 1 | Yes (1) |
| 589 | SESN1 | sestrin 1 | 2 | 1 | 1 | Yes (1) |
| 590 | SESN2 | sestrin 2 | 2 | 1 | 1 | Yes (1) |
| 591 | ULK1 | unc-51 like autophagy activating kinase 1 | 2 | 2 | 0 | Yes (1) |
| 592 | PRDM1 | PR domain containing 1, with ZNF domain | 1 | 1 | 0 | Yes (1) |
| 593 | Shortenedtelomeres | No node name found | 2 | 1 | 1 | Yes (1) |
| 594 | IL13 | interleukin 13 | 1 | 0 | 1 | No |